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PRODUCT

Discover our full range of services"From Molecule to Medicine".

QUALITY & SERVICE

Test, research, develop, and improve products to make them better, safer, and more accessible.

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INDUSTRY-CHANGING
INNOVATIONS

Continuous improvement of Calcium 

Gluconate performance and process

LONG-TERM
PARTNER

Partnering to develop the 

right solution for your business

HIGH RELIABLE
API

Produced to be more robust 

and reliable than the competition

ON-CALL EXPERT
SUPPORT

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and running 24/7

WHY CHOOSE US

Test, research, develop, and improve products to make them better, safer, and more accessible.

Pharma Services Overview

A wide range of pharmaceutical company clients, partners and collaborators

International pharmaceutical companies

Start-up to mid-tier biotech companies

Food additive companies

Health food companies

Whom We Serve

Why Clients Come to Ruibang

We have decades of pharmaceutical R&D expertise

We meet or exceed client timelines

We offer direct communication with project scientists

We have a client focus that accommodates change


What We Do

Formulation development


Analytical methods development


Regulatory and drug manufacturing

GMP clinical supply manufacturing

Commercial manufacturing of specialty pharmaceuticals

Strategic consulting services tailored for your needs

Biotech and pharma companies

International companies

Put Our Experience To Work For You.

60+ Years Of Experience In The Pharmaceutical

Production, Technology, Equipment, Raw materials

Active Pharmaceutical Ingredient (API)

Calcium gluconate is a mineral supplement. It is the form of calcium most widely used in the treatment of hypocalcemia.


Calcium Gluconate is white in colour and is available in the form of crystalline powder or granules. Calcium Gluconate is found to be highly effective in the treatment of calcium deficiencies

General

Introduction

Calcium Gluconate is extensively used in the treatment of Calcium deficiency, both for oral and parenteral administration.


It is also used as an oral antidote for fluorine and oxalic acid poisoning and as a substitute for fruit acids in the manufacture of fruit jellies and baking powders and in the preparation of homogeneous pastes like dentifrices and metal polishes; ferrous gluconate which can be readily made from Calcium Gluconate is used in the treatment iron deficiency and in tonic compositions.


Aluminum Gluconate has potential use as a tanning agent.

Process

The waste mycelium of Penicillium chrysogenum HA-10 (obtained at the end of penicillin fermentation), or a 24-hr-old freshly grown vegetative inoculum of this organism, was found to utilize glucose for the production of calcium gluconate by submerged fermentation in shake flasks.


Calcium Gluconate is produced by the electrolytic oxidation of Glucose dissolved in sodium bromide solution used as electrolyte in a cell having graphite electrodes.


Gluconic acid formed is neutralized by the suspended Calcium Carbonate present in the electrolyte. Calcium Gluconate formed in the electrolyte is recovered by cooling the mother liquor obtained after recovery of the product is continuously reused in further batches.

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